Lifestyle Medicine and the Methylome

Kara Fitzgerald, ND, IFMCP

Presentation Overview:

DNA methylation plays a central, potentially lasting (and heritable) regulatory role in health and disease. Aberrant methylation patterns resulting in regions of hyper- and hypomethylation influence the course of most, if not all, chronic disease. In cancer, it is understood that epimutations outpace genetic mutations 10:1. It is also understood that lifestyle factors can profoundly influence epigenetic methylation expression. Integrative and Functional Medicine clinicians, in employing a systems approach to care, are arguably best suited to optimize their patient’s genetic expression.

Learning Objectives:

  1. DNA methylation overview and importance
  2. DNA methylation, aging and healthspan
  3. The wide range of factors that influence methylation status
  4. Practical interventions to support balanced methylation, including supplements, diet and lifestyle
  5. What’s next? Assessing the methylome in clinical practice