Lifestyle Medicine and the MethylomeKara Fitzgerald, ND, IFMCP
DNA methylation plays a central, potentially lasting (and heritable) regulatory role in health and disease. Aberrant methylation patterns resulting in regions of hyper- and hypomethylation influence the course of most, if not all, chronic disease. In cancer, it is understood that epimutations outpace genetic mutations 10:1. It is also understood that lifestyle factors can profoundly influence epigenetic methylation expression. Integrative and Functional Medicine clinicians, in employing a systems approach to care, are arguably best suited to optimize their patient’s genetic expression.
- DNA methylation overview and importance
- DNA methylation, aging and healthspan
- The wide range of factors that influence methylation status
- Practical interventions to support balanced methylation, including supplements, diet and lifestyle
- What’s next? Assessing the methylome in clinical practice